Drug-Food Interactions with a Focus on Mediterranean Diet

نویسندگان

چکیده

There is a growing interest among people in western countries for adoption of healthier lifestyle habits and diet behaviors with one the most known ones to be Mediterranean (Med-D). Med-D linked daily consumption food products such as vegetables, fruits, whole grains, seafood, beans, nuts, olive oil, low-fat derivatives limited meat or full fat products. well-known promote well-being lower risk chronic conditions cardiovascular diseases, diabetes, metabolic syndrome. On other hand bioactive constituents foods may interfere drugs’ pharmacological mechanisms, modulating clinical outcome leading drug-food interactions (DFIs). This review discusses current evidence that are included within Med-Dand available scientific data suggest potential contribution DFIs impact on therapeutic outcome. Most cases refer modulation absorption metabolism foods’ carrier-mediated transport enzymatic well synergistic antagonistic effects enhance reduce effect some drugs. Adherence can improve disease management overall well-being, but specific should consumed caution so not hinder therapy Proper patient education consultation from healthcare providers important avoid any conflicts side due clinically significant DFIs.

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ژورنال

عنوان ژورنال: Applied sciences

سال: 2022

ISSN: ['2076-3417']

DOI: https://doi.org/10.3390/app122010207